| Autor: |
Andrew C. Li, Yi Hong Ong, Andreea Dimofte, Timothy C. Zhu, Theresa M. Busch |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
17th International Photodynamic Association World Congress. |
| DOI: |
10.1117/12.2525624 |
| Popis: |
Determination of in-vivo tissue optical properties for anal photodynamic therapy (PDT) is challenging due to the light integrating-sphere effect in an enclosed cylindrical cavity. We developed a model for optical properties determination for anal PDT from measurements of light fluence rate inside a cylindrical cavity submerged in tissue-mimicking liquid phantoms. Measurements are performed in a set of phantoms with known optical properties (μa = 0.1-0.9 cm-1) and (μs’ = 5.5-16.5 cm-1) and the primary and scatter light fluence rates are determined. We developed a forward empirical model to relate scatter light fluence rate measured in an enclosed cylindrical geometry to the surrounding tissue optical properties in tissue-simulating liquid phantoms. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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