Optimized bio-inspired kernels with twin support vector machine using low identity sequences to solve imbalance multiclass classification

Autor: Rd. Rohmat Saedudin, Baraa Wasfi Salim, Shahreen Kasim, Rohayanti Hassan, S.K. Guramand, Rohaizan Ramlan
Rok vydání: 2019
Předmět:
Zdroj: Journal of Environmental Biology. 40:563-576
ISSN: 2394-0379
0254-8704
Popis: The function of enzymes is performed differently depending on their bio-chemical mechanisms and important to the prediction of protein structure and function. In order to overcome the weaknesses of imbalance data distribution in subclasses prediction we proposed Bio-Twin Support Vector Machine (Bio–TWSVM). The TWSVM approach as also allow for kernel optimization where in this study we have introduced the bio-inspired kernels such as the Fisher, spectrum and mismatch kernels which at the same time incorporate the biological information regarding the protein evolution in the classification process.
Databáze: OpenAIRE