A near-infrared BODIPY-based fluorescent probe for ratiometric and discriminative detection of Hg2+ and Cu2+ ions in living cells
| Autor: | Yan Huang, Hui-ya Tan, Jin-wu Yan, Chun-Feng Li, Fenggang Liu, Liyao Zheng, Zhi-Zhou He, Wen-Jing Shi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
inorganic chemicals
biology 010401 analytical chemistry Near-infrared spectroscopy 02 engineering and technology 021001 nanoscience & nanotechnology biology.organism_classification Photochemistry 01 natural sciences Fluorescence 0104 chemical sciences Analytical Chemistry Ion HeLa chemistry.chemical_compound chemistry Intramolecular force Naked eye Absorption (chemistry) BODIPY 0210 nano-technology |
| Zdroj: | Talanta. 198:390-397 |
| ISSN: | 0039-9140 |
| DOI: | 10.1016/j.talanta.2019.02.012 |
| Popis: | A near-infrared distyryl boron dipyrromethene-based sensor bearing one bis(1,2,3-triazole)amino receptor has been synthesized. This probe selectively and quickly binds to Hg2+ and Cu2+ ions in CH3CN/H2O (5:1 v/v) and exhibits remarkably blue-shifted absorption and fluorescence bands due to the inhibition of the intramolecular charge transfer process. The fluorescence changes of this probe upon binding to Hg2+ or Cu2+ ion are totally different, undergoing a ratiometric fluorescence enhancement (for Hg2+) or a fluorescence quenching (for Cu2+) mechanism. The corresponding vivid color changes can be easily seen by the naked eye. This probe was further introduced into Hela cells for living cell imaging and found to discriminate Hg2+ and Cu2+ ions through two near-infrared fluorescence emission channels. These overall results indicate that this Click-derived near-infrared BODIPY-based probe is potentially useful for ratiometric and discriminative detection of Hg2+ and Cu2+ ions in solutions and living cells. |
| Databáze: | OpenAIRE |
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