Structure and hypotensive effect of flavonoid glycosides in lemon peelings. Part II

Autor:	Yoshiharu Matsubara, Katsumi Yokoi, Hiroyasu Kumamoto, Yoshitomi Iizuka, Kozo Okamoto
Rok vydání:	1985
Předmět:	chemistry.chemical_classification Chromatography Flavonoid glycosides Chemistry Butanol Extraction (chemistry) Medicine (miscellaneous) Glycoside Body weight chemistry.chemical_compound Chemistry (miscellaneous) Lead subacetate Apigenin Sugar Food Science Biotechnology
Zdroj:	Journal of the agricultural chemical society of Japan. 59:677-682
ISSN:	1883-6844 0002-1407
DOI:	10.1271/nogeikagaku1924.59.677
Popis:	An attempt was made to isolate hypotensive substances from hot water extracts of lemon peels. Eight flavonoid glycosides were isolated by repeated chromatography after extraction with butanol and treated with lead subacetate. Their structures were established by UV, MS, 1H-NMR and 13C-NMR spectroscopy, and sugar analysis to be : 6, 8-di-C-glucosyldiosmetin (8), 6-C-glucosyldiosmetin (9), 8-C-glucosyldiosmetin (10), isovitexine (11), apigenin 7-[6-O-α-rhamnosyl-β-glucose] (12), limocitrin 3-0-{[3-hydroxy-3-methylglutarate(1→2)]-β-glucose} (13), limocitrin 3-0-{[5-α-glucosyl-3-hydroxy-3-methylglutarate(1→2)]-β-glucose} (14) and limocitrol 3-O-{[5-α-glucosyl-3-hydroxy-3-methylglutarate(1→2)]-β-glucose} (15). Each component was intravenously injected into SHR-SP rats (1.0mg/100g body weight), and 8 was found to lower blood pressure. Among these compounds, 13, 14 and 15 were new flavonol glycosides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::183115366b1f35d3972ee47243e8d58f https://doi.org/10.1271/nogeikagaku1924.59.677 Zobrazit plný text záznamu