Combined Role of Two Tryptophane Residues of α-Factor Pheromone

Autor: Eun Young Hong, Nam Joo Hong
Rok vydání: 2013
Předmět:
Zdroj: Bulletin of the Korean Chemical Society. 34:600-608
ISSN: 0253-2964
DOI: 10.5012/bkcs.2013.34.2.600
Popis: ]α-factoramide ( 10) were found to have antagonistic activity. Analogs 3 and 6 showed greater antagonistic activity thananalogs 8 and 10. Key Words : α-Factor, Amide analogs, S. cerevisiae, ActivityIntroductionThe α-factor, tridecapeptide (WHWLQLKPGQPMY), issecreted by Saccharomyces cerevisiae MATa haploid cellsand recognized by a receptor that is coded by gene (STE2)which is expressed in S. cerevisiae MATa haploid cells.
Databáze: OpenAIRE