Tongue-Based Procedures in Treating Refractory Obstructive Sleep Apnea in Down Syndrome Patients: A Systematic Review and Meta-Analysis
| Autor: | Caitlin Priest, Michael T Chung, Paul B. Lee, Edward T. Chang, Jonathan Waxman, Jordyn Lucas, Ho-Sheng Lin, Jared Johnson |
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| Rok vydání: | 2021 |
| Předmět: |
Down syndrome
Pediatrics medicine.medical_specialty business.industry medicine.disease respiratory tract diseases Obstructive sleep apnea 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure stomatognathic system Refractory Tongue Meta-analysis Medicine 030223 otorhinolaryngology business 030217 neurology & neurosurgery |
| Zdroj: | FACE. 2:65-70 |
| ISSN: | 2732-5016 |
| DOI: | 10.1177/2732501621992447 |
| Popis: | Objective: There is a high prevalence of obstructive sleep apnea (OSA) in pediatric and adult Down Syndrome (DS) patients that is refractory to adenotonsillectomy and continuous positive airway pressure. Newer treatment modalities have emerged with improved outcomes. The objective is to provide an updated systematic review and meta-analysis to analyze the clinical outcomes of OSA in pediatric and adult DS patients with hypoglossal nerve stimulation using Inspire, midline posterior glossectomy plus lingual tonsillectomy (MPG + LT), and combined genioglossus advancement plus radiofrequency (GGS + RF). Methods: A comprehensive literature search of PubMed and Google Scholar was performed followed by a meta-analysis. Studies with preoperative and post-operative Apnea Hypopnea Index (AHI) values were included with patients serving as their own control. Results: Across 5 studies, 56 patients were analyzed. The mean reduction in AHI was statistically significant before vs. after procedure ( P |
| Databáze: | OpenAIRE |
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