Necrolytic acral erythema as a manifestation of Crohn’s disease and celiac disease - A report of two cases
Autor: | Anza Khader, Sukumarakurup Sreekanth, Shiny Padinjarayil Manakkattu, Nimmi John |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Crohn's disease medicine.diagnostic_test business.industry Hepatitis C virus 030231 tropical medicine Necrolytic acral erythema Recurrent diarrhea Disease Hepatitis C medicine.disease medicine.disease_cause Dermatology digestive system diseases 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biopsy Vomiting Medicine medicine.symptom business |
Zdroj: | Journal of Skin and Sexually Transmitted Diseases. 2:130-133 |
ISSN: | 2582-3175 |
DOI: | 10.25259/jsstd_17_2020 |
Popis: | Necrolytic acral erythema (NAE) is considered as a diagnostic marker of hepatitis C infection. Here, we report two cases of NAE in Crohn’s disease and celiac disease. Both the patients were seronegative for hepatitis C virus. The first case presented with recurrent diarrhea, weight loss, bullae on hyperpigmented plaque over extremities and gastrointestinal endoscopy and biopsy consistent with Crohn’s disease. The second case presented with recurrent diarrhea, vomiting, vesiculopustules and scaly plaques over extremities and duodenal biopsy diagnostic of celiac disease. NAE presents as papules and plaques with bullae over extremities, but tend to spare palms and soles. Our first patient had lesions on sole and the second patient had pustular lesions. To the best of our knowledge, there are no available reports of association of NAE with Crohn’s disease or celiac disease. |
Databáze: | OpenAIRE |
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