ChemInform Abstract: Synthesis of N-Glycosylated Pyridines as New Antiviral Agents

Autor:	Y. A. Abbas, Adel M. Attia, M. M. Abbasi, E. S. Ibrahim, M. A. Elbadawi, Galal H. Elgemeie
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry Replication (statistics) Nucleic acid Human immunodeficiency virus (HIV) medicine Glycoside General Medicine medicine.disease_cause Virology
Zdroj:	ChemInform. 26
ISSN:	0931-7597
DOI:	10.1002/chin.199547279
Popis:	A series of 3-cyanopyridine glycosides have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) replication in MT-4 cells. Among the 3-cyanopyridine glycosides 6-(p-methylphenyl) and 6-(p-aminophenyl) were the most selective inhibitors of HIV replication.
Databáze:	OpenAIRE
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