A facile and convenient synthesis of 5-trifluoromethyl-4-pyridazinones from aldehyde dialkylhydrazones

Autor:	Toshiaki Ikemura, Ryōichi Masuda, Yasuhiro Kamitori, Yoshiko Mori, Masaru Hojo
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Trifluoromethyl Intramolecular reaction Silica gel Organic Chemistry Hydrazone Biochemistry Haloketone Aldehyde chemistry.chemical_compound chemistry Pentafluoropropionic anhydride Drug Discovery Organic chemistry Enone
Zdroj:	Tetrahedron Letters. 34:5135-5138
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)60696-2
Popis:	Several 5-trifluoromethyl-4-pyridazinones were conveniently synthesized by silica gel-mediated cyclization reaction of 1,1,1,2,2-pentafluoroalkan-3,4-dione 4-dialkylhydrazones prepared from aldehyde dialkylhydrazones and pentafluoropropionic anhydride.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::17aa907a78af5440e3ac5a0103891537 https://doi.org/10.1016/s0040-4039(00)60696-2 Zobrazit plný text záznamu