Clinical and demographic features of patients with stroke and atrial fibrillation

Autor: D.A. Ospanova, D.M. Akpanova, A.T. Mussagaliyeva, B S Zhussupov, S.F. Berkinbayev
Rok vydání: 2018
Předmět:
Zdroj: Kardiologiia. 17:48-57
ISSN: 0022-9040
Popis: Background. Stroke takes the second place among all causes for cardiovascular death and the first place in mortality and disability among other nervous system diseases. Atrial fibrillation (AF) is presently is a commonly recognized, independent risk factor for ischemic stroke, which fivefold increases the risk of an unfavorable outcome. Prevention of stroke is a complicated medical and social challenge. Aim. To study AF prevalence among patients with stroke/ transient ischemic attack (TIA) who had received an anticoagulant therapy before hospitalization. Materials and methods. A retrospective analysis of case reports was performed for patients diagnosed with acute cerebrovascular disease and TIA who had received a therapy from January, 2013 through December, 2015 (n=7921). From these case reports, 849 case reports of patients with concurrent AF were selected. Results. In patients with stroke/TIA, the AF incidence was 10.72%. Risk assessment using the CHA 2 DS 2 -VASc scale showed that the percentage of low-risk patients (score 0) was 0.8%, intermediate risk patients (score 1) - 5.3%, and high-risk patients (score ≥2) - 93.8%; 4.7% of patients with AF received preven tive therapy for thromboembolic complications. The death rate of patients with AF and stroke/TIA was 15.78% whereas in-hospital death rate of patients without AF was 7.01%. Therefore, AF is a statistically significant risk factor of in-hospital mortality for patients with stroke/TIA (OR=2.485, 95% CI: 2.023-3.053, p
Databáze: OpenAIRE