Atherosclerosis and Sudden Death and Their Relationship to Visceral Fat in Men Under 40 With no History of Cardiovascular Diseases and Normal BMI

Autor: Zeynalabedin Malekpoor, Azade Memarian, Mostafa Jafarzadeh, Leyla Abdolkarimi, Farrokh Taftachi, Maryam Ameri
Rok vydání: 2016
Předmět:
Zdroj: Research in Cardiovascular Medicine.
ISSN: 2251-9580
2251-9572
DOI: 10.5812/cardiovascmed.40162
Popis: In addition to abdominal fat thickness, the question arises whether other visceral fat deposits, including epicardial and mesenteric fat, even in men with a normal body mass index (BMI < 30 and acceptable waist/hip ratio [WHR]) can lead to atherosclerosis and cardiac hypertrophy. The present study was conducted to compare the distribution of visceral fat between men under 40 who experienced sudden death due to coronary artery obstruction and a control group who have passed from traffic accidents in Tehran. Autopsy samples were collected from a total of 94 men and divided into 2 groups of 47 men. The case group (sudden death from coronary obstruction) and the control group (death due to traffic accidents) were matched in terms of age, height and weight. BMI and waist/hip ratio were within the acceptable range in both groups. Neither of the groups had cardiovascular or other diseases. The findings of the study showed a greater thickness of subcutaneous abdominal fat around the navel and a higher epicardial fat, mesenteric weight, heart mass and heart mass to height ratio in the group of men who died due to coronary artery obstruction. Accordingly, even in seemingly healthy men under 40 with no obese men (with normal BMI and acceptable WHR), the accumulation of internal visceral fat such as subcutaneous abdominal fat around the navel and epicardial and mesenteric fat can contribute to coronary artery obstruction and cardiac hypertrophy.
Databáze: OpenAIRE