Vaccine response after pneumococcal vaccination in allogeneic hematopoietic stem cell transplant recipients

Autor: Halle Cheplowitz, Nimish Patel, Alexander Kim, Cathy Logan, Nancy Law, Divya Koura, Nina Haste, Katherine Medley, Julie Trinh, Tyler Sanders, Mahnaz Taremi, Ila M Saunders
Rok vydání: 2023
Předmět:
Zdroj: Journal of Oncology Pharmacy Practice. :107815522311657
ISSN: 1477-092X
1078-1552
DOI: 10.1177/10781552231165733
Popis: Current guidelines for vaccination in allogeneic hematopoietic stem cell transplant (HCT) recipients recommend initiation of pneumococcal vaccination series three to six months post-HCT, with most data supporting initiation at six months due to a more robust immune response. This single-center, retrospective, observational chart review aimed to evaluate the impact of initiating the pneumococcal vaccine series at three months post-HCT compared to six months post-HCT. The primary endpoints were defined as a percentage of patients with a serologic response of >1 and >1.3 µg/mL for over 50% of the defined serotypes. Outcomes showed no difference in immunologic response between the two groups.
Databáze: OpenAIRE