Neurophysiological and ultrasonographic comparative study of autonomous nervous system in patients suffering from fibromyalgia and generalized anxiety disorder

Autor: Ioannis Michopoulos, Marianna Papadopoulou, Christos Moschovos, Elisabeth Chroni, Apostolos Papapostolou, Eleni Bakola, Vasilios G. Masdrakis, Georgios Tsivgoulis
Rok vydání: 2021
Předmět:
Zdroj: Neurological Sciences. 43:2813-2821
ISSN: 1590-3478
1590-1874
DOI: 10.1007/s10072-021-05606-3
Popis: Fibromyalgia (FM) and generalized anxiety disorder (GAD) share common clinical features: they both affect women more than men, their diagnosis is based solely on clinical criteria, and some of the symptoms such as anxiety, aches and muscle tension, sleep disorders, and cognitive dysfunction occur in both diseases. For both conditions, an underlying dysregulation of the autonomic nervous system (ANS) has been proposed. The aims of this study were to investigate ANS dysfunction in FM and GAD and compare them with controls. Sympathetic skin response (SSR) from palm and sole and cross-sectional area (CSA) of bilateral vagus nerves (VN) were measured in 28 healthy controls, 21 FM patients, and 24 GAD patients. CSA of VN was significantly smaller in FM patients (right: 1.97 ± 0.74mm2, left: 1.75 ± 0.65 mm2) and GAD patients (right: 2.12 ± 0.97mm2, left: 1.71 ± 0.86 mm2) compared to controls (right: 3.21 ± 0.75 mm2, left: 2.65 ± 1.13 mm2, p
Databáze: OpenAIRE