Psychological and sympatho-adrenal status in patients with cystic acne

Autor:	Evangelos D. Papakonstantinou, T. Michas, Sophia Georgala, Kleopatra H. Schulpis
Rok vydání:	1999
Předmět:	medicine.medical_specialty business.industry Dermatology Norepinephrine (medication) Infectious Diseases Mood Endocrinology Epinephrine Internal medicine Severity of illness Catecholamine Medicine Anxiety Sympathoadrenal system medicine.symptom business Isotretinoin medicine.drug
Zdroj:	Journal of the European Academy of Dermatology and Venereology. 13:24-27
ISSN:	1468-3083 0926-9959
DOI:	10.1111/j.1468-3083.1999.tb00839.x
Popis:	Background Patients with cystic acne (CA) frequently report feeling self conscious, anxiety and social isolation. Methods Mood characteristics as well as self-esteem scores of 38 patients with CA were evaluated before and after 30 days treatment with isotretinoin. A high pressure, liquid chromatography method was used for the evaluation of catecholamines (epinephrine (E) and nor-epinephrine (NE)) in the blood of the patients at the time of the study and in controls (n=30) after their psychological testing. Moreover, E and NE were measured in the blood of eight healthy volunteers before and after 1 month ‘treatment’ with the drug. Results The CA subjects evidenced anxiety and high catecholamine plasma levels (E=98.0±0.8 pg/ml, NE=250.8±56.6 pg/ml) before treatment compared to controls (E=71.8±23.0 pg/ml, NE=190.0±52 pg/ml, P Conclusions It is suggested that not only the psychological status is influenced in subjects with CA but also their sympathoadrenal system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::17414c09079d9f56b18a5793593785b1 https://doi.org/10.1111/j.1468-3083.1999.tb00839.x Zobrazit plný text záznamu Plný text