ACUTE ISCHEMIC STROKE IN WOMEN: EFFICACY OF THE FREE RADICAL SCAVENGER EDARAVONE
| Autor: | Maryna A Trishchynska, Tetiana M Povietkina, Oleg A Loskutov, Oleksandr A Halushko, Dmytro O Dziuba, Alla D Vitiuk, Yuriy P Vdovychenko |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Enolase Glasgow Coma Scale Neurological examination General Medicine Free radical scavenger Gastroenterology chemistry.chemical_compound chemistry Internal medicine Reference values medicine Edaravone Prospective cohort study business Acute ischemic stroke |
| Zdroj: | Wiadomości Lekarskie. 74:72-76 |
| ISSN: | 0043-5147 |
| DOI: | 10.36740/wlek202101114 |
| Popis: | OBJECTIVE The aim: To investigate the effectiveness of usage of the free radical scavenger Edaravone in the therapy of women with AIS. PATIENTS AND METHODS Materials and methods: A prospective study was conducted of 48 women with AIS, divided into two groups. Patients in the first group (n = 36) were treated with edaravone 30 mg twice a day intravenously. Neuroprotectors were not used in the control group (n = 12). Clinical-instrumental and neurological examination (Glasgow scale (SCG), FOUR, NIHSS, and neuronspecific enolase (NSE) levels) were performed on all patients. RESULTS Results: The mean FOUR score in the 1th group increased from 11.04±0.85 to 15.47±0.63 points against 11.39±0.56 to 13.46±1.49 in the control group (pp |
| Databáze: | OpenAIRE |
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