The reactions of copper-dibromodifluoromethane-amide systems with alcohols
| Autor: | James H. Clark, Martin A. McClinton, Robert John Blade |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Organic Chemistry
chemistry.chemical_element Substrate (chemistry) Biochemistry Copper Inorganic Chemistry Benzylic alcohol chemistry.chemical_compound chemistry Amide Environmental Chemistry Organic chemistry Dibromodifluoromethane Chelation Reaction system Physical and Theoretical Chemistry Solvent effects |
| Zdroj: | Journal of Fluorine Chemistry. 59:257-267 |
| ISSN: | 0022-1139 |
| DOI: | 10.1016/s0022-1139(00)82418-5 |
| Popis: | 1,1,1-Trifluoro-2-arylethanes can be prepared by the trifluoromethyldehydroxylation of benzyl alcohols using the copper-dibromodifluoromethane-amide reaction system, although the yields are low. The mechanism of the reaction may involve chelation of the substrate to copper so that α-substituted benzyl alcohols and most other alcohols are unreactive. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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