Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina
| Autor: | Lisandro J González, Jennifer S. Fernandez, Jasmine Martinez, German Matias Traglia, Mark Raymond Adams, Carolina Lopez, Maria Soledad Ramirez, Robert A. Bonomo, Alejandro J. Vila, Fernando Pasteran, Christine Liu, Fanny Huang, Alejandra Corso, Ezequiel Albornoz |
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| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
0303 health sciences biology 030306 microbiology Chromosome biochemical phenomena metabolism and nutrition Acinetobacter bacterial infections and mycoses biology.organism_classification Genome DNA sequencing Metallo β lactamase Microbiology Acinetobacter baumannii 03 medical and health sciences Infectious Diseases Plasmid Pharmacology (medical) Gene 030304 developmental biology |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 64 |
| ISSN: | 1098-6596 0066-4804 |
| Popis: | A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying bla NDM-1 . Genome sequencing revealed that most were Acinetobacter baumannii , whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. bla NDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non- A. baumannii strains. |
| Databáze: | OpenAIRE |
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