IDENTIFICATION AND COMPARATIVE GENOMIC ANALYSIS OF SIGNALING AND REGULATORY COMPONENTS IN THE DIATOMTHALASSIOSIRA PSEUDONANA
| Autor: | Micaela S. Parker, Mak A. Saito, Chris Bowler, Andrew E. Allen, Angela Falciatore, Sacha Coesel, Masood Z. Hadi, Kirk E. Apt, Marc Heijde, Assaf Vardi, Gregory J. Pazour, Kamel Jabbari, Edda Rayko, J. Casey Lippmeier, Uma Maheswari, Anthony Chiovitti, Anton Montsant, Daniel S. Rokhsar, Alessandra De Martino, Kimberlee Thamatrakoln, Diego Martinez, Aubrey K. Davis, Manuela Mangogna, Magali Siaut, E. Virginia Armbrust, John A. Berges, Todd W. Lane |
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| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Journal of Phycology. 43:585-604 |
| ISSN: | 1529-8817 0022-3646 |
| DOI: | 10.1111/j.1529-8817.2007.00342.x |
| Popis: | Diatoms are unicellular brown algae that likely arose from the endocytobiosis of a red alga into a single-celled heterotroph and that constitute an algal class of major importance in phytoplankton communities around the globe. The first whole-genome sequence from a diatom species, Thalassiosira pseudonana Hasle et Heimdal, was recently reported, and features that are central to diatom physiology and ecology, such as silicon and nitrogen metabolism, iron uptake, and carbon concentration mechanisms, were described. Following this initial study, the basic cellular systems controlling cell signaling, gene expression, cytoskeletal structures, and response to stress have been cataloged in an attempt to obtain a global view of the molecular foundations that sustain such an ecologically successful group of organisms. Comparative analysis with several microbial, plant, and metazoan complete genome sequences allowed the identification of putative membrane receptors, signaling proteins, and other components of central interest to diatom ecophysiology and evolution. Thalassiosira pseudonana likely perceives light through a novel phytochrome and several cryptochrome photoreceptors; it may lack the conserved RHO small-GTPase subfamily of cell-polarity regulators, despite undergoing polarized cell-wall synthesis; and it possesses an unusually large number of heat-shock transcription factors, which may indicate the central importance of transcriptional responses to environmental stress. The availability of the complete gene repertoire will permit a detailed biochemical and genetic analysis of how diatoms prosper in aquatic environments and will contribute to the understanding of eukaryotic evolution. |
| Databáze: | OpenAIRE |
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