Plasmodium fieldi: Observations on the Hackeri and ABI Strains in Macaca mulatta Monkeys and Mosquitoes

Autor:	Allison Williams, JoAnn S. Sullivan, William E. Collins, McWilson Warren, G. Gale Galland, John W. Barnwell
Rok vydání:	2009
Předmět:	biology Anopheles medicine.disease biology.organism_classification Plasmodium fieldi Virology Plasmodium Apicomplexa Infectious Diseases Malaria transmission Anopheles dirus medicine Parasite hosting Parasitology Malaria
Zdroj:	The American Journal of Tropical Medicine and Hygiene. 80:739-744
ISSN:	1476-1645 0002-9637
DOI:	10.4269/ajtmh.2009.80.739
Popis:	Macaca mulatta monkeys infected with the Hackeri strain of Plasmodium fieldi had maximum parasite counts ranging from 1,300 to 301,320/microL. In 43 intact animals infected with the ABI strain, the maximum parasite counts ranged from 672 to 57,189/microL (median = 15,100/microL); in 46 splenectomized monkeys, the maximum parasite count ranged from 660 to 350,000/microL (median = 52,245/microL). Transmission through Anopheles dirus mosquitoes was obtained on 11 occasions with pre-patent periods of 9-14 days. Relapses occurred between two and eight times during a 1-year period. P. fieldi has potential for testing prophylactic and radical curative drugs.
Databáze:	OpenAIRE
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