Detection of urinary lactoferrin as an indicator of urinary tract infection in girls
| Autor: | Nabeel Elia Waheda, Dik J. Kok, Mohammed Hassan Fatah |
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| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Zanco Journal of Medical Sciences. 20:1485-1489 |
| ISSN: | 1995-5596 1995-5588 |
| DOI: | 10.15218/zjms.2016.0048 |
| Popis: | Background and objective: Lactoferrin (LF) is an iron-binding protein that is related in structure to transferrin. It is considered to be a part of the innate immune system. This study aimed to assess the role of urinary lactoferrin (LF) as an indicator for diagnosis of urinary tract infection among girls. Methods: This study was conducted on girls suffering from UTI. Urine samples were tested for Lactoferrin before and after two months of the treatment using ELISA technique. Results: Urine specimens were collected from 25 girls with mean age ± SD of 6 ± 3 years without UTI as a control group (C) and 25 girls with mean age ± SD of 5.3 ± 3.18 years diagnosed as suffering from UTI (T1) followed by a set of 25 specimens after two months (T2). The mean concentration of urinary LF ± SD was 670 ± 319 ng/ml in the specimens of control group whereas it was 1387 ± 509 in the specimens of girls with UTI during the infection (T1) and 885 ± 268 after two months (T2). The mean concentrations of urinary LF during the infection (T1) were significantly (P |
| Databáze: | OpenAIRE |
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