A Case–Control Study of Follicular Fluid Cytokine Profiles in Women with Diminished Ovarian Reserve

Autor: Hao Tang, Quinton S. Katler, Haw Han Yen, Weirong Shang, Brianne Petritis, Heather S. Hipp, Jing-Qiao Lu, Anna K. Knight, Ruo Pan Huang, Sina Abhari, Sabrina A. Gerkowicz, Ying-Qing Mao, Laurie J. McKenzie, Alicia K. Smith
Rok vydání: 2021
Předmět:
Zdroj: Reproductive Sciences. 29:2515-2524
ISSN: 1933-7205
1933-7191
DOI: 10.1007/s43032-021-00757-2
Popis: Ovarian reserve is an important determinant of a woman’s reproductive potential, and women with diminished ovarian reserve (DOR) often seek in vitro fertilization (IVF). The underlying etiology of DOR is unknown, but follicular fluid cytokine concentrations likely play a role in follicular development and maturation. The present study seeks to investigate the expression of cytokines in follicular fluid (FF) of women with DOR undergoing IVF and explore correlated functional pathways. One hundred ninety-four women undergoing ovarian stimulation were recruited at the time of oocyte retrieval. Women were classified as having DOR if they met one or more of the following criteria: AMH 10 mIU/ml, and/or AFC
Databáze: OpenAIRE