Acoustic Radiation Force Impulse Imaging for Assessing Liver Fibrosis Preoperatively in Infants With Biliary Atresia: Comparison With Liver Fibrosis Biopsy Pathology
| Autor: | Sheng-Li Gu, Luan Li, Ya-Qing Chen, Jing Fang, Xiao-Ying Wang, Fen Gao |
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| Rok vydání: | 2017 |
| Předmět: |
Pathology
medicine.medical_specialty Cirrhosis Radiological and Ultrasound Technology medicine.diagnostic_test Receiver operating characteristic business.industry medicine.disease Preoperative care 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Biliary atresia Fibrosis Liver biopsy Biopsy medicine 030211 gastroenterology & hepatology Radiology Nuclear Medicine and imaging Radiology business Acoustic radiation force impulse imaging |
| Zdroj: | Journal of Ultrasound in Medicine. 36:1571-1578 |
| ISSN: | 0278-4297 |
| Popis: | Objectives The purpose of this study was to investigate the diagnostic performance of acoustic radiation force impulse (ARFI) in assessing liver fibrosis preoperatively in infants with biliary atresia (BA). Methods A total of 50 consecutive infants with BA and 50 healthy infants who underwent ARFI examination were recruited. Siemens Acuson S2000 in Virtual Touch Quantification mode (Siemens Medical Solutions, Mountain View, CA) was used to measure shear wave speeds (SWSs). All infants with BA underwent a liver biopsy within 3 days after ARFI imaging. The liver fibrosis stages of specimens were defined according to the Batts-Ludwig scoring system. The correlation analysis was performed between SWSs and pathological findings. Cut-off values were determined using receiver operating characteristic (ROC) curves. Results The mean SWS in the BA group was significantly higher than controls (mean ± standard deviation): 1.89 ± 0.45 versus 1.12 ± 0.06 m/s; P |
| Databáze: | OpenAIRE |
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