The Effects of Aqueous Extract of Boswellia Serrata on Memory Impairment Induced by Lipopolysaccharide

Autor:	Samaneh Borooni, Fahimeh Nourbakhsh, Parisa Behshood, Elahe Tajbakhsh
Rok vydání:	2020
Předmět:	Aqueous extract chemistry.chemical_compound biology Lipopolysaccharide chemistry Traditional medicine Boswellia serrata Memory impairment biology.organism_classification
Zdroj:	International Journal of Medical Laboratory.
ISSN:	2423-3714 2423-3706
DOI:	10.18502/ijml.v7i4.4802
Popis:	Background and Aims: The therapeutic effects of the olibanum, the resin of Boswellia serrata (B. serrata) from the Burseraceae family in inflammatory disease have been reported. There are more than 200 active ingredients in this resin, including Boswellic acid. It is proposed that aqueous extract of B. serrata can improve memory impairment induced by cerebral inflammation result in the administration of lipopolysaccharide (LPS). Materials and Methods: In this study, after the treatment of rats with LPS, brain toxicity induction was performed, and finally, the behavioral tests were evaluated. Following cerebral inflammation induction and treatment, behavioral performance biochemistry tests and molecular methods were assessed in all groups. Results: LPS administration increased the duration and distance to find the platform in the Morris water maze test compared to the control group in 5 days (p
Databáze:	OpenAIRE
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