ChemInform Abstract: Chlorotrimethylsilane-Mediated Formation of ω-Allyl Esters of Aspartic and Glutamic Acids
| Autor: | Gilles A. Lajoie, Shadreck Mzengeza, Peter J. Belshaw |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
chemistry.chemical_classification
endocrine system diseases organic chemicals nutritional and metabolic diseases food and beverages General Medicine Amino acid chemistry.chemical_compound chemistry Reagent Yield (chemistry) Organic chemistry Allyl alcohol hormones hormone substitutes and hormone antagonists |
| Zdroj: | ChemInform. 22 |
| ISSN: | 0931-7597 |
| DOI: | 10.1002/chin.199115258 |
| Popis: | The protection of the ω-carboxylic function of aspartic and glutamic acids by an allyl ester is advantageous because of its orthogonality with most protecting groups and its compatibility with a number of reagents. In this communication we describe a simple method using chlorotrimethylsilane in the presence of allyl alcohol which gives exclusively the ω-allyl esters of both aspartic and glutamic acids in excellent yield. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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