The effects of non-andrological medications on erectile dysfunction: a large single-center retrospective study

Autor: R. Mazzilli, V. Zamponi, F. Mangini, S. Olana, G. Defeudis, A. Faggiano, D. Gianfrilli
Rok vydání: 2023
Předmět:
Zdroj: Journal of Endocrinological Investigation.
ISSN: 1720-8386
DOI: 10.1007/s40618-023-02011-9
Popis: Purpose To evaluate the association among andrological diseases at the first outpatient visit and the medications taken by patients for other comorbidities, as well as the differential impact between specific medication and relative comorbidities. Methods This is a single-center retrospective study based on subjects who referred to the Andrology Unit with a well-defined andrological diagnosis. Results A total of 3752 subjects were studied (mean age ± DS 46.2 ± 16.5 years). A total of 19 categories of andrological diseases and 110 type of medications for other comorbidities were identified. ED was the most frequent andrological pathology at the first andrological examination (28.7%), followed by infertility (12.4%). The couple of variables that were statistically significant in the univariate association analysis (p Conclusion ED is significantly associated with antihypertensive, antihyperglycemic, lipid-lowering, psychotropic drugs’ intake. Anyway, ED appears to be more related to the diseases than to the specific therapies. The definitive cause/effect relationship should be established based on future prospective studies.
Databáze: OpenAIRE