Development of a cell co-cultivation system based on protein magnetic membranes, using a MSLA 3D printer
| Autor: | Igor Blatov, S. Rodionov, I. V. Zubarev, A. S. Minin |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
business.industry
Manufacturing process Computer science 0206 medical engineering Biomedical Engineering 3D printing 02 engineering and technology 021001 nanoscience & nanotechnology 020601 biomedical engineering Computer Science Applications 3d printer Membrane 0210 nano-technology business Biological system Biotechnology |
| Zdroj: | Bioprinting. 23:e00150 |
| ISSN: | 2405-8866 |
| Popis: | The ability to reproduce in vitro cell-cell interactions and transitions across different functional states warrants the development of model systems for studying various physiological and pathological processes. To analyze intercellular interactions, it is imperative to co-cultivate distinct cell types. Such model systems are widely used for reproducing the in vivo conditions of cell-cell interactions. This article reviews existing models and proposes a new 3D printing-derived cell co-cultivation system based on levitation under a magnetic field in the culture medium of a magnetic protein membrane with cells. The 3D printing method allows to flexibly and quickly adjust the manufacturing process to the needs of a particular laboratory. Such protein membranes can be made in any laboratory using a 3D printer and widely available general laboratory reagents. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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