Creatina fosfocinasa MB como marcador diagnóstico de disfunción miocárdica en pacientes pediátricos con quemadura eléctrica
| Autor: | Fernando D. Solís-Cordero, Mary S. Saavedra-Pacheco, Yaneth Martínez-Tovilla, Mariana Lee Miguel-Sardaneta, Manuel Gil-Vargas |
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| Rok vydání: | 2020 |
| Předmět: |
Body surface area
medicine.medical_specialty Ejection fraction medicine.diagnostic_test business.industry Physical examination Diagnostic marker Electrical burn Hypokinesia Internal medicine Pediatrics Perinatology and Child Health cardiovascular system medicine Cardiology In patient medicine.symptom Creatine Phosphokinase-MB business |
| Zdroj: | Boletín Médico del Hospital Infantil de México. 77 |
| ISSN: | 0539-6115 |
| Popis: | Background The decrease of the left ventricular ejection fraction (LVEF) as consequence of a ventricular dysfunction is reported in cardiac alterations secondary to electrical injury. The focused cardiac ultrasound (FoCUS) helps to complete the clinical examination because it allows a faster non-invasive evaluation, and provides information that contributes to make better therapeutic decisions, especially those for patients in critical condition. The objective of this study was to explore the utility of creatine phosphokinase MB (CPK-MB) as a diagnostic tool of myocardial dysfunction in patients from 6 to 18 years old with electrical burn. Methods From November 2018 to August 2019, we conducted a transversal analytic study of 10 children with electric burn (6 to 18 years of age), in whom the percentage of LVEF was obtained through the FoCUS protocol in the first 24 hours after injury. Results We found 10 cases of electrical burn injury, eight males and two females, with an average of 13 years of age. Eighty percent of these cases showed a slight decrease in LVEF (45-59%). When performing the FoCUS protocol, myocardial hypokinesia was reported in seven patients. We observed a moderate correlation between LVEF and CPK-MB levels (r = -0.671), and no correlation between LVEF and body surface area affected by the electrical burn. Conclusions The cardiac ultrasound influences decision making to improve the prognosis of these patients. |
| Databáze: | OpenAIRE |
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