Assessment of Myocardial Contractility by SonR Sensor in Patients Undergoing Cardiac Resynchronization Therapy

Autor:	Paola Attanà, Paolo Pieragnoli, Marco Chiostri, Stefania Sacchi, Alessandro Paoletti Perini, Giuseppe Ricciardi, Luigi Padeletti, Gino Grifoni
Rok vydání:	2016
Předmět:	medicine.medical_specialty Ejection fraction business.industry medicine.medical_treatment Cardiac resynchronization therapy Hemodynamics General Medicine 030204 cardiovascular system & hematology medicine.disease Contractility 03 medical and health sciences 0302 clinical medicine Blood pressure Heart failure Internal medicine Cardiology Medicine Sinus rhythm In patient 030212 general & internal medicine Cardiology and Cardiovascular Medicine business
Zdroj:	Pacing and Clinical Electrophysiology. 39:268-274
ISSN:	0147-8389
DOI:	10.1111/pace.12795
Popis:	BACKGROUND SonR sensor signal correlates well with myocardial contractility expressed in terms of left ventricular (LV) dP/dt max. The aim of our study was to evaluate the changes in myocardial contractility during isometric effort in heart failure patients undergoing cardiac resynchronization therapy (CRT) with right atrial SonR sensor. METHODS Thirty-one patients (19 men, 65 ± 7 years, LV ejection fraction [LVEF] 28% ± 5%, in sinus rhythm) were implanted with a CRT-defibrillator (CRT-D) device equipped with SonR sensor, which was programmed in VVI mode at 40 beats/min. Twenty-four hours after implantation, each patient underwent a noninvasive hemodynamic evaluation at rest and during isometric effort, including: (1) measurement of beat-to-beat endocavitary SonR signal; (2) echocardiographic assessment; and (3) continuous measurement of blood pressure with Nexfin method (BMEYE, Amsterdam, the Netherlands). The following contractility parameters were considered: (1) mean value of beat-to-beat SonR signal; (2) mean value of LV dP/dt by Nexfin system; and (3) fractional shortening (FS) by echocardiography. RESULTS At the third minute of the isometric effort, mean value of SonR signal significantly increased from baseline (P < 0.001). Similarly, mean value of both LV dP/dt by Nexfin and FS significantly increased compared to the resting condition (P < 0.001; P < 0.001). While in 27 (88%) patients SonR signal increased at the third minute of the isometric effort, in four (12%) patients SonR signal decreased. In these patients, both LV dP/dt by Nexfin and FS consensually decreased. CONCLUSIONS In CRT patients, SonR sensor is able to detect changes in myocardial contractility in a consensual way like noninvasive methods such as Nexfin system and echocardiography.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::16bb62c3ebb41fe885012c78192bcda7 https://doi.org/10.1111/pace.12795 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.