Comparison of the effects of combined nicotine replacement therapy vs. cigarette smoking in males
| Autor: | Heidi Haustein, Knut-Olaf Haustein, Thomas Rasmussen, Jörn Krause, Nicholas Cort |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
business.industry
Cholesterol media_common.quotation_subject Public Health Environmental and Occupational Health Abstinence Nicotine replacement therapy Nicotine chemistry.chemical_compound chemistry Anesthesia mental disorders Toxicity behavior and behavior mechanisms Medicine TCPO Adverse effect business Cotinine media_common medicine.drug |
| Zdroj: | Nicotine & Tobacco Research. 5:195-203 |
| ISSN: | 1469-994X 1462-2203 |
| Popis: | This open study assessed the effects of nicotine replacement therapy (NRT) on the normalizing of exhaled carbon monoxide (CO), transcutaneous partial oxygen tension (tcpO(2)), plasma cotinine and thiocyanate levels, and cardiovascular risk markers in abstinent subjects compared with untreated smokers after 4, 8, 12, and 26 weeks. The trial enrolled 197 subjects in two parallel groups: 164 subjects who received NRT (patch plus gum) for 12 weeks and 33 untreated smokers (controls). At 26 weeks, 123/164 participants in the treatment group had completed the study; 51/123 (41.5%) sustained abstinence from smoking, whereas 72/123 (58.5%) had relapsed. Changes in cotinine (abstainers: 291.6 ng/ml at baseline vs. 27.3 ng/ml at week 26; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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