Development and Internal Validation of a Prediction Model for In-Hospital Mortality in Geriatric Patients With a Hip Fracture
| Autor: | Henk Jan Schuijt, R. Marijn Houwert, Diederik P.J. Smeeing, J. Han Hegeman, Detlef van der Velde, Franka S Würdemann, Olivia Geraghty, Michael J. Weaver |
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| Rok vydání: | 2020 |
| Předmět: |
030222 orthopedics
Hip fracture Pediatrics medicine.medical_specialty In hospital mortality business.industry MEDLINE 030208 emergency & critical care medicine Hip fracture surgery General Medicine Evidence-based medicine medicine.disease 03 medical and health sciences 0302 clinical medicine Cohort medicine Orthopedics and Sports Medicine Surgery Internal validation business Prospective cohort study |
| Zdroj: | Journal of Orthopaedic Trauma. 34:656-661 |
| ISSN: | 0890-5339 |
| DOI: | 10.1097/bot.0000000000001851 |
| Popis: | OBJECTIVE To develop and validate a prediction model for in-hospital mortality in patients with hip fracture 85 years of age or older undergoing surgery. DESIGN A multicenter prospective cohort study. SETTING Six Dutch trauma centers, level 2 and 3. PARTICIPANTS Patients with hip fracture 85 years of age or older undergoing surgery. INTERVENTION Hip fracture surgery. MAIN OUTCOME MEASUREMENTS In-hospital mortality. RESULTS The development cohort consisted of 1014 patients. In-hospital mortality was 4%. Age, male sex, American Society of Anesthesiologists classification, and hemoglobin levels at presentation were independent predictors of in-hospital mortality. The bootstrap adjusted performance showed good discrimination with a c-statistic of 0.77. CONCLUSION Age, male sex, higher American Society of Anesthesiologists classification, and lower hemoglobin levels at presentation are robust independent predictors of in-hospital mortality in patients with geriatric hip fracture and were incorporated in a simple prediction model with good accuracy and no lack of fit. LEVEL OF EVIDENCE Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence. |
| Databáze: | OpenAIRE |
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