Metastatic melanoma of unknown primary origin, A case report

Autor:	Tsukasa Haneda, Daisuke Horiguchi, Reiko Wakui, Yasushi Tomita, Yoshihiro Katoh, Fujiko Fukatsu-Yokoo
Rok vydání:	2001
Předmět:	Chemotherapy Pathology medicine.medical_specialty Lung business.industry Melanoma medicine.medical_treatment medicine.disease Axilla medicine.anatomical_structure medicine Abdomen Lymph Skin cancer business Tamoxifen medicine.drug
Zdroj:	Skin Cancer. 16:27-32
ISSN:	1884-3549 0915-3535
DOI:	10.5227/skincancer.16.27
Popis:	We report a rare case of melanoma of unknown primary origin with visceral and skin metastases. A 24-year-old man noted itchy tumors in the right lower leg and abdomen one month before admission. The tumors were biopsied and diagnosed as metastatic melanoma. Various examinations revealed many metastatic tumors in the lung, the lymph nodes and the skin, but no primary resion. We tried chemotherapy so-called DAV-Feron (DTIC, ACNU, VCR, IFN-β) first, with successful regression of lymph nodes in the axilla. After cutaneous nodules increased, we next tried DAC-Tam (DTIC, ACNU, CDDP, Tamoxifen), and they began to regress two months after starting the chemotherapy. Although the lung metastatic lesions were slowly growing, other metastatic tumors in the lymph nodes and the skin were regressed by the daily administration of tamoxifen for 18 months since his admission.[Skin Cancer (Japan) 2001; 16: 27-32]
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::169b2604b0aaa4370d2d83f9bb0910be https://doi.org/10.5227/skincancer.16.27 Zobrazit plný text záznamu