DOENÇA DE JORGE LOBO: RELATO DE CASO E REVISÃO DE LITERATURA
| Autor: | Jovarci Motta, Eduardo Toffoli Pandini, Hudson Silva Andrade, Aloísio Falqueto, Alexandre Neves Furtado, Patrícia Henriques Lyra Frasson |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
General Immunology and Microbiology biology medicine.diagnostic_test business.industry Medical record Public Health Environmental and Occupational Health Lacazia Physical examination Disease medicine.disease biology.organism_classification Dermatology Surgery Infectious Diseases Keloid medicine Lobomycosis Histopathology business Fluconazole medicine.drug |
| Zdroj: | Revista de Patologia Tropical. 42 |
| ISSN: | 1980-8178 0301-0406 |
| DOI: | 10.5216/rpt.v42i4.27931 |
| Popis: | Introduction and objectives: Jorge Lobo’s disease is a rare chronic disease caused by the fungus Lacazia loboi, characterized by keloid lesions on the skin. The objective is to perform a review of the literature and report the first case of Jorge Lobo’s disease treated at the University Hospital Cassiano Antonio Moraes (HUCAM). Materials and methods: The study data were obtained retrospectively from the analysis and systematic review of the medical records of a patient with Jorge Lobo’s disease identified in HUCAM. Case Report: A male patient aged 37 years was referred to HUCAM in April 2010 presenting with keloid lesions and a previous diagnosis of lobomycosis by histopathology examination. On December 2011 a partial removal of the lesions with grafting was performed. Three months later, there was recurrence of lobomycosis on the grafted tissue. In June 2012 drug treatment with clofazimine associated with fluconazole was started. The lack of satisfactory clinical response after two months meant that the disease was considered beyond cure. Discussion and literature review: lobomycosis is an endemic disease in the brazilian Amazon and other humid tropical areas of Central and South America, and its transmission occurs by inoculation of the fungus through breaks in the skin. Diagnosis is made by clinical examination and histopathologiy or cytology The choice of therapy varies with the extent of lesions. However, none of the therapies described in the literature is fully effective. Conclusion: In this case, the two main therapeutic approaches failed, and the disease was considered incurable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|