Polymer-bound TBTU as a new solid-supported reagent for peptide synthesis

Autor:	José M Soriano, Carmen Nájera, David J. Dodsworth, Rafael Chinchilla
Rok vydání:	2000
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Chemistry law Reagent Organic Chemistry Drug Discovery Peptide synthesis Polymer Biochemistry Combinatorial chemistry Filtration law.invention
Zdroj:	Tetrahedron Letters. 41:2463-2466
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)00180-5
Popis:	A new polymer-supported TBTU (P-TBTU) has been prepared from polystyrene-bound 1-hydroxybenzotriazole (P-HOBT) and used efficiently as a solid-supported reagent for peptide-coupling reactions, and is even effective with wet solvents. The P-HOBT can be recovered by simple filtration and reused for the preparation of new P-TBTU.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::169ac530e291c0dfd6a54f76478a414c https://doi.org/10.1016/s0040-4039(00)00180-5 Zobrazit plný text záznamu Full Text from ScienceDirect