Transvaginal parametrial needle biopsy for detection of postirradiation recurrent cancer of the cervix
| Autor: | Jose M. Sala, William D. Johnston, Eugene M. Bricker, Marvin J. Lopez, George J. Fuchs, William G. Kraybill |
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| Rok vydání: | 1988 |
| Předmět: |
Cancer Research
medicine.medical_specialty Systemic disease Pelvic exenteration medicine.diagnostic_test Parametrial business.industry medicine.medical_treatment Cancer medicine.disease Surgery Radiation therapy medicine.anatomical_structure Oncology Biopsy medicine Intravaginal administration business Cervix |
| Zdroj: | Cancer. 61:275-278 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19880115)61:2<275::aid-cncr2820610214>3.0.co;2-j |
| Popis: | During the 27-year period from 1956 to 1982, transvaginal parametrial needle biopsies were performed on 76 patients clinically suspected of harboring postirradiation recurrent cervical cancer without mucosal lesions suitable for biopsy under direct vision. Needle biopsies indicated cancer in 41 patients, resulting in 20 abdominal explorations. Eleven of these patients underwent total pelvic exenteration. Three patients survived longer than 5 years. Among 35 patients whose biopsies did not suggest cancer, eight proved to be false-negative as demonstrated by later progression of local and systemic disease. The remaining 27 patients in whom biopsies showed negative results were cured by radiation therapy. Bleeding, easily controlled by vaginal packing, occurred in one patient; in another, a pelvic abscess was drained 7 days after the biopsy. The authors conclude that when judiciously performed, transvaginal parametrial needle biopsy has a high diagnostic yield (89%) with minimal morbidity (2.6%). Its application during the careful observation of patients suspected to harbor recurrence may increase the operability rate and may offer selected patients a chance for cure by radical pelvic surgery. |
| Databáze: | OpenAIRE |
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