18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial

Autor:	Lennart Thurfjell, Ian Law, Allan R. Andersen, Koen Van Laere, Rik Vandenberghe, David J. Brooks, Christopher Buckley, Christine Bastin, Lennart Minthon, Eric Salmon, Steen G. Hasselbalch, Guy Bormans, Adrian Ivanoiu, Alex Korner, Gaëtan Garraux, Natalie Nelissen, Gill Farrar, Eric Triau, Rikard Owenius
Rok vydání:	2010
Předmět:	Oncology medicine.medical_specialty Pathology Amyloid medicine.diagnostic_test business.industry medicine.disease chemistry.chemical_compound Neurology chemistry Neuroimaging Positron emission tomography Internal medicine Medical imaging medicine Dementia Neurology (clinical) Alzheimer's disease Pittsburgh compound B business Florbetaben
Zdroj:	Annals of Neurology. 68:319-329
ISSN:	0364-5134
DOI:	10.1002/ana.22068
Popis:	The most widely studied positron emission tomography ligand for in vivo beta-amyloid imaging is (11)C-Pittsburgh compound B ((11)C-PIB). Its availability, however, is limited by the need for an on-site cyclotron. Validation of the (18)F-labeled PIB derivative (18)F-flutemetamol could significantly enhance access to this novel technology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1686f3a1fbeb4c1e0ae53a5476366da8 https://doi.org/10.1002/ana.22068 Zobrazit plný text záznamu Plný text