A Facile and General Synthesis of 2β-Aminosteroids

Autor:	Nimmanapalli Pulla Reddy, Xianming Hu, Dingshan Zhou, Wenjin Xu, Qifeng Zhu, Xianbing Ke, Hao Hu
Rok vydání:	2009
Předmět:	Aminolysis chemistry Organic Chemistry Regioselectivity Organic chemistry chemistry.chemical_element Zinc Catalysis
Zdroj:	Synthesis. 2009:1255-1260
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0028-1088037
Popis:	A facile and general synthesis of 2β-aminosteroids in high yields from 2,3a-epoxy-5a-androstan-17-one by regioselective aminolysis is developed using a zinc chloride/water catalytic system. The reaction is successful with both aliphatic and aromatic amines as well as with azoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1676a3b1b5af496fcf320dd2434726f4 https://doi.org/10.1055/s-0028-1088037 Zobrazit plný text záznamu