PREDICTIVE FACTORS ASSOCIATED WITH SUCCESSFUL VARICOCELE REPAIR
| Autor: | Masami Takeyama, Minoru Koga, Hiroshi Kiuchi, Yukiomi Namba, Kenji Nishimura, Kiyomi Matsumiya, Akihiko Okuyama, Toshiaki Hirai, Akira Tsujimura |
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| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | The Japanese Journal of Urology. 96:480-486 |
| ISSN: | 1884-7110 0021-5287 |
| DOI: | 10.5980/jpnjurol1989.96.480 |
| Popis: | Purpose To determine pretreatment parameters which predict improvements following varicocele repaire in semen quality. Materials and methods We retrospectively evaluated a total of 139 infertile patients who underwent varicocelectomy from February 1995 to March 2000. A logistic regression analysis was performed to identify parameters associated with improvements in semen quality. Parameters evaluated included varicocele grade, age, testicular volume, serum testosterone, liteinizing hormone (LH), follicle-stimulating hormone (FSH), preoperative sperm density and sperm motility. Results Of 139 patients 71 (51.0%) improved sperm concentration and 59 (42.4%) improved sperm motility postoperatively. Overall, median sperm density significantly increased from 10 x 10(6)/ml preoperatively to 30 x 10(6)/ml postoperatively. Sperm motility also significantly increased 33% to 45%. In logistic regression analysis, varicocele grade (odds ratio [OR] = 5.7; 95% confidential interval [CI : 1.9-17), FSH level ([OR] = 0.76; [CI]: 0.60-0.96) and sperm motility ([OR] = 1.03; [CI]: 1.0-1.1) were independent predictive factors for improvement in sperm concentration. Conclusion Varicocelectomy improves sperm concentration and motility. Our data suggest that patients with grade 3 varicocele, low serum FSH level and high sperm motility are more likely to benefit from varicocele repair in sperm concentration. |
| Databáze: | OpenAIRE |
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