Ethanol
| Autor: | Marta Chagas Monteiro, Sabrina C. Cartágenes, Luanna Melo Pereira Fernandes, C.S.F. Maia, Rui Daniel Prediger, Rafael Rodrigues Lima, E. Fontes de Andrade |
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| Rok vydání: | 2017 |
| Předmět: |
Motor disorder
Chemistry Central nervous system Neurotoxicity medicine.disease medicine.disease_cause 030227 psychiatry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure medicine Anxiety medicine.symptom Neurotransmitter Neuroscience 030217 neurology & neurosurgery Neuroinflammation Oxidative stress Depression (differential diagnoses) |
| DOI: | 10.1016/b978-0-12-805373-7.00020-7 |
| Popis: | Alcohol-induced brain disorders have been reported for many decades. Ethanol (EtOH) presents amphiphilicity properties that permit the fluidibility across the biological barriers. The EtOH kinetics depends on the gender and age that elicit different brain susceptibility damage. The exact mechanisms that underlie such central nervous system (CNS) disruption due to EtOH is not well understood; however, neuroinflammation, oxidative stress, and neurotransmitter system disorder processes may play a role. Therefore, the principal CNS effects described are anxiety, depression, motor disorder, and cognitive impairment after chronic ethanol exposure. This chapter summarizes many of the alcohol kinetics differences, the possible mechanisms of CNS damage, the main behavioral/CNS function, and the structures affected by chronic alcohol exposure. |
| Databáze: | OpenAIRE |
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