Array-Comparative Genomic Hybridization/Microarray Analysis: Interpretation of Copy Number Variants

Autor:	Herman E. Wyandt, Golder N. Wilson, Vijay S. Tonk
Rok vydání:	2017
Předmět:	stomatognathic diseases Copy number analysis Representation oligonucleotide microarray analysis Human genome Copy-number variation Computational biology Biology Genome Exome sequencing Virtual karyotype Comparative genomic hybridization
Zdroj:	Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis ISBN: 9789811030345
DOI:	10.1007/978-981-10-3035-2_9
Popis:	Two revolutionary advances in molecular biology have enabled scanning of the entire human genome for genetic variation: 1. Array-comparative genomic hybridization-microarray analysis (aCGH, CMA, microarray analysis, referred to henceforth as aCGH) that identifies altered DNA dosage. 2. Whole genome or exome sequencing (WGS or WES) that identifies nucleotide sequence changes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::15fd4f41ffaf1f4ed933f80e647992a4 https://doi.org/10.1007/978-981-10-3035-2_9 Zobrazit plný text záznamu