Variation in Angiostrongylus cantonensis infection in definitive and intermediate hosts in Hawaii, a global hotspot of rat lungworm disease
| Autor: | Lisa Kaluna, Susan I Jarvi, Shane R. Siers, Israel L. Leinbach, Chris N. Niebuhr |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Rattus exulans 030231 tropical medicine Zoology Snail Biology biology.organism_classification medicine.disease Angiostrongylus cantonensis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases Nematode biology.animal Parmarion martensi Angiostrongyliasis medicine Parasite hosting Animal Science and Zoology Parasitology Lungworm |
| Zdroj: | Parasitology. 148:133-142 |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s003118202000164x |
| Popis: | Angiostrongylus cantonensis (rat lungworm) is a tropical and subtropical parasitic nematode, with infections in humans causing angiostrongyliasis (rat lungworm disease), characterized by eosinophilic meningitis. Hawaii has been identified as a global hotspot of infection, with recent reports of high infection rates in humans, as well as rat definitive and snail intermediate hosts. This study investigated variation in A. cantonensis infection, both prevalence and intensity, in wild populations of two species of rats (Rattus exulans and R. rattus) and one species of snail (Parmarion martensi). An overall infection prevalence of 86.2% was observed in P. martensi and 63.8% in rats, with R. exulans (77.4%) greater than R. rattus (47.6%). We found infections to vary with environmental and host-related factors. Body mass was a strong predictor of infection in all three species, with different patterns seen between sexes and species of rats. Infection prevalence and intensity for R. exulans were high in May 2018 and again in February 2019, but generally lower and more variable during the intervening months. Information on sources of variability of infection in wild host populations will be a crucial component in predicting the effectiveness of future disease surveillance or targeted management strategies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|