ChemInform Abstract: Synthesis of 5′-C-Hydroxyalkylthymidines and Their Incorporation into Oligodeoxynucleotides

Autor:	Patrick J. Middleton, Yi-Zhong An, Guangyi Wang
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Nucleic acid Nanotechnology General Medicine Thymidine Combinatorial chemistry
Zdroj:	ChemInform. 28
ISSN:	0931-7597
DOI:	10.1002/chin.199729220
Popis:	5′-C-Hydroxymethyl-, 5′-C-hydroxyethyl, and 5′-C-hydroxypropylthymidine derivatives were prepared through four synthetic routes, which constitute an approach to introduce hydroxyalkyl of different lengths at C5′ of thymidine. 5′-C-hydroxymethyl- and 5′-C-hydroxypropylthymidines were converted to the corresponding phosphoramidites and incorporated into oligodeoxynucleotides. © 1997 Elsevier Science Ltd.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::15c1b21c17fd6ab942df82f7f943d7a8 https://doi.org/10.1002/chin.199729220 Zobrazit plný text záznamu Plný text