Vaginal colonization and vulvovaginitis by Candida species in pregnant women from Northern of Colombia
| Autor: | Martha Puello Hoyos, Ana María Bello Trujillo, Paola Suárez Álvarez Paola Suárez Álvarez, Alicia Irene Arechavala, Marlene Durán Lengua, Gregorio Young Castro |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
education.field_of_study
biology business.industry Population Physiology medicine.disease biology.organism_classification Vaginal estrogen Candida tropicalis Vaginal Lubricant Anesthesiology and Pain Medicine Candida krusei medicine Bacterial vaginosis business Candida albicans education Fluconazole medicine.drug |
| Zdroj: | Archivos de Medicina (Manizales). 18:51-59 |
| ISSN: | 2339-3874 1657-320X |
| Popis: | Objective: identify the vaginal colonizing Candida species and VVC species, predisposing factors and susceptibility against fluconazole in pregnant women attending gynecological outpatient of a maternal clinic in Cartagena (Colombia). Vulvovaginal candidiasis (VVC) is a common infection that affects a large proportion of women of childbearing age. It is estimated that about 75% of healthy women have had at least one episode of VVC in her life. Vaginal colonization by Candida spp. can vary from 10 to 17% and this is increased by 35% during pregnancy. The epidemiological behavior of Candida in VVC tends to be variable and this will depend on the level of vaginal estrogens, conditions of immunosuppression or chronicity of the process. Materials and Methods: the laboratory study included the direct examination of vaginal swabs, by fresh and differential staining of smears and cultures. The isolated species were identified by phenotypic tests and by multiplex PCR and CLSI M27-A3 microdilution method was used to evaluate susceptibility to fluconazole. Results: the frequent clinical diagnosis of bacterial vaginosis, did not correspond with the laboratory diagnosis in which predominated the intermediate biota. The results showed Candida albicans as the most common isolated species, followed by Candida tropicalis and Candida krusei . Candida colonization occurred in 71.4% and 28.6% of the population was diagnosed with vaginal candidiasis. All isolates were susceptible to fluconazole. Conclusion: The most common factors for colonization were related to clothing and for vaginal candidiasis to the use of vaginal lubricants. |
| Databáze: | OpenAIRE |
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