Synthesis of Chalcogen-Containing Nanocomposites of Selenium and Tellurium with Arabinogalactan and a Study of Their Toxic and Antimicrobial Properties
| Autor: | M. K. Borovskaya, M. A. Novikov, I. A. Graskova, L. M. Sosedova, A. I. Perfileva, E. A. Titov, V. A. Vokina, T. V. Kon’kova, Boris A. Trofimov, Rukavishnikov Vs, N. L. Yakimova, G. B. Borovskii, M. V. Lesnichaya, Boris G. Sukhov |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Nanocomposite
biology Chemistry General Engineering chemistry.chemical_element 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Antimicrobial biology.organism_classification 01 natural sciences Acute toxicity 0104 chemical sciences Chalcogen Arabinogalactan General Materials Science 0210 nano-technology Cytotoxicity Clavibacter michiganensis Selenium Nuclear chemistry |
| Zdroj: | Nanotechnologies in Russia. 13:290-294 |
| ISSN: | 1995-0799 1995-0780 |
| Popis: | This paper reports the synthesis of nanocomposites of selenium and tellurium on a polymer matrix: arabinogalactan. Their physicochemical and biological properties are presented in detail. Studies of the parameters of acute toxicity and sex sensitivity to the nanocomposite of selenium and arabinogalactan show the following. The nanocomposite is characterized as a substance with a low acute toxicity hazard in the acute intragastric route of entry; no differences in the sex sensitivity of animals are revealed. The concentration dependences of the cytotoxicity of composites for human HEp-2 and ECV-304 cell cultures, as well as the green monkey kidney fibroblasts (Vero B), are studied during the investigation of biological properties of the nanocomposites of Te and Se with arabinogalactan. It is found that the Te and Se nanocomposites exhibit a different dependence of cytotoxicity on the concentration in all cultures studied. The nanocomposite of arabinogalactan with elemental selenium is shown to have a bactericidal effect against the causative agent of the ring rot of potato Clavibacter michiganensis subsp. sepedonicus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink