Fatal Rabies Encephalitis despite Appropriate Post-Exposure Prophylaxis

Autor:	Martin Shill, Steven D. Miller, Roy D. Baynes
Rok vydání:	1987
Předmět:	Pediatrics medicine.medical_specialty business.industry medicine.medical_treatment General Medicine Immunotherapy medicine.disease Virology Virus Vaccination Rabies vaccine Medicine Rabies Viral disease Post-exposure prophylaxis business Encephalitis medicine.drug
Zdroj:	New England Journal of Medicine. 316:1257-1258
ISSN:	1533-4406 0028-4793
DOI:	10.1056/nejm198705143162006
Popis:	RABIES encephalitis was one of the earliest diseases known.1 Because rabies is uniformly fatal, every attempt must be made to prevent invasion of the virus. Since the introduction of a rabies vaccine in 1885, post-exposure vaccination has formed the cornerstone of prophylaxis after the bite of a rabid animal. Occasional cases of failure of prophylaxis followed the use of the early duck-embryo vaccine and rabies immune globulin.1 In several of these cases, however, unacceptably long delays had preceded the institution of therapy.1 In one case, in which duck-embryo vaccine and rabies immune globulin were promptly administered, a suboptimal immune response . . .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::15ae3f69f35dd2188d295a9fe26ca8f1 https://doi.org/10.1056/nejm198705143162006 Zobrazit plný text záznamu