Histochemical Localization of Alcohol Dehydrogenase Activities in the Livers of Mice, Rats, Hamsters, and Guinea-Pigs
| Autor: | Manabu Yoshida, Toshimitsu Watabiki, Yutaka Okii, Takuma Tokiyasu, Sumitaka Yoshimura, Atsushi Akane |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Physiology Hamster Cell Biology Biology digestive system Biochemistry digestive system diseases Pathology and Forensic Medicine Centrilobular Zone Staining Distribution pattern medicine biology.protein Immunohistochemistry Lobules of liver Alcohol dehydrogenase |
| Zdroj: | ACTA HISTOCHEMICA ET CYTOCHEMICA. 30:381-387 |
| ISSN: | 1347-5800 0044-5991 |
| Popis: | The hepatic lobular localization of alcohol dehydrogenase (ADH) activity was examined histochemically in mice, rats, hamsters and guinea-pigs with the nitro blue tetrazolium method. In the mouse liver, the ADH activity was localized mainly in the centrilobular zone. In the rat and hamster livers, it was observed throughout the lobule, with increased centrilobular staining. Interestingly, in the guinea-pig liver, it was found to be evenly localized in both the centrilobular and periportal zones, with little or no midlobular staining. These findings show that the distribution pattern of ADH activity in the hepatic lobule of the guinea-pigs differs strikingly from that of the mice, rats and hamsters. |
| Databáze: | OpenAIRE |
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