PhI(OAc)2-mediated trifluoromethylthiolation/oxidative cyclization of ynamides

Autor:	Shixuan Su, Zhipeng Yan, Li Yuan, Xingyuan Ye, Jingyang Wang, Guangke He
Rok vydání:	2021
Předmět:	Oxidative cyclization Chemistry Reagent Organic Chemistry Physical and Theoretical Chemistry Biochemistry Medicinal chemistry Quaternary carbon
Zdroj:	Organic & Biomolecular Chemistry. 19:8746-8753
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d1ob01642c
Popis:	A PhI(OAc)2-mediated trifluoromethylthiolation/oxidative cyclization of ynamides with the Shen reagent has been established herein, providing a facile access to CF3S-substituted oxazolidine-2,4-diones bearing a quaternary carbon center in 38-85% yields with chemoselectivities of up to 99/1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1591f801149c5bca6a3c3d10e1c68195 https://doi.org/10.1039/d1ob01642c Zobrazit plný text záznamu