EPR Diagnostics of D,L-Polylactide Porous Matrices Formed in Supercritical CO2
| Autor: | T. A. Ivanova, N. A. Chumakova, Peter S. Timashev, Viktor N Bagratashvili, Elena N. Golubeva, N. N. Vorobieva |
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| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Materials science Supercritical carbon dioxide Dopant 02 engineering and technology Polymer 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Supercritical fluid 0104 chemical sciences law.invention Spin probe Paramagnetism Chemical engineering chemistry law Physical and Theoretical Chemistry 0210 nano-technology Electron paramagnetic resonance Porous medium |
| Zdroj: | Russian Journal of Physical Chemistry B. 12:1255-1260 |
| ISSN: | 1990-7923 1990-7931 |
| Popis: | The regularities of formation of D,L-polylactide porous matrices in supercritical CO2 environment with simultaneous impregnation with paramagnetic biologically active 4-hydroxy-2,2,6,6-tetramethylpiperidine- 1-oxyl (TEMPOL) was studied using spin probe electron paramagnetic resonance (EPR) and optical microscopy. The dependence of the average and local concentration of a dopant on impregnation conditions was assessed. The resulting matrices meet important requirements for porous materials for tissue engineering. Considering that impregnation of a polymer with a paramagnetic compound makes it possible to study the uniform distribution of a dopant in a sample at macroscopic and microscopic levels and to study a structure of a polymer matrix, EPR spectroscopy is a promising method for studying porous polymeric materials formed under supercritical conditions. |
| Databáze: | OpenAIRE |
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