Study of Blood Selenium Level in Thyroid Pathologies by Instrumental Neutron Activation Analysis

Autor:	S. Benamer, M. A. Benamar, L. Aberkane
Rok vydání:	2006
Předmět:	endocrine system medicine.medical_specialty endocrine system diseases Chemistry General Chemical Engineering Thyroid Cancer chemistry.chemical_element Metabolism medicine.disease medicine.anatomical_structure Endocrinology Selenium deficiency Internal medicine medicine Thyroid hormone synthesis Risk factor Neutron activation analysis Instrumentation Selenium General Environmental Science
Zdroj:	Instrumentation Science & Technology. 34:417-423
ISSN:	1525-6030 1073-9149
DOI:	10.1080/10739140600648837
Popis:	Selenium deficiency constitutes a risk factor for several pathologies (congestive cardiomyopathie, cancer, etc.). It was shown, recently, that selenium is implied in thyroid metabolism. It constitutes the catalytic site of the enzymes intervening in thyroid hormone synthesis. In the present work, we determined concentrations of selenium in total blood of 39 patients suffering from thyroid pathologies (hyperthyroidism [HEP], hypothyrodism [HOP], simple goiter [SG]), and 29 normal controls using instrumental neutron activation analysis (INAA). The blood selenium concentrations of patients suffering from hyperthyroidism was 142.56±20.25 µg/L of total blood, which is significantly lower than that of normal controls (206.72±17.98 µg/L. p≤0.05). No significant differences were observed in the concentrations of Se in hypothyroidism (184.26±20.77 µg/L) and simple goiter groups (160.47±25.76 µg/L).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1551f0fa14320f8cb53056a7ef413ebc https://doi.org/10.1080/10739140600648837 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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