A pair of novel 2,3-seco cafestol-type diterpenoid epimers from the twigs of Tricalysia fruticosa

Autor:	Chuan-Pu Shen, Ling-Yi Kong, Ming-Hua Yang, Jian-Guang Luo
Rok vydání:	2015
Předmět:	Rubiaceae biology Chemistry Stereochemistry Organic Chemistry Cafestol biology.organism_classification Biochemistry Terpenoid Tricalysia Drug Discovery medicine Epimer Two-dimensional nuclear magnetic resonance spectroscopy medicine.drug
Zdroj:	Tetrahedron Letters. 56:1328-1331
ISSN:	0040-4039
Popis:	A pair of 2,3-seco cafestol-type diterpenoid epimers, frutilactones A (1) and B (2) were isolated from twigs of Tricalysia fruticosa. Their structures were elucidated by comprehensively employing spectroscopic methods (MS and 1D/2D NMR) and ECD. Their inhibitory effects on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated, and a possible biogenetic pathway was also proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1549eed1b9f926d52ac6c6e47b953cf2 https://doi.org/10.1016/j.tetlet.2015.01.178 Zobrazit plný text záznamu Full Text from ScienceDirect