Treatment of canine sinonasal aspergillosis with clotrimazole infusion in patients with cribriform plate lysis
| Autor: | J. A. Stanton, D. L. Davignon, Stephen C. Barr, M. L. Miller, P. Johnson |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty 040301 veterinary sciences Clotrimazole business.industry 030106 microbiology Retrospective cohort study 04 agricultural and veterinary sciences Cribriform plate Neurologic Effect Aspergillosis medicine.disease Surgery 0403 veterinary science 03 medical and health sciences medicine Clinical significance Neurologic examinations In patient Small Animals business medicine.drug |
| Zdroj: | Journal of Small Animal Practice. 59:411-414 |
| ISSN: | 0022-4510 |
| Popis: | Objective To describe the treatment of sinonasal aspergillosis with topical 1% clotrimazole solution in dogs with cribriform plate lysis. Materials and methods This retrospective study includes data retrieval from medical records of dogs with sinonasal aspergillosis and cribriform plate lysis that underwent topical treatment with 1% clotrimazole solution. Results Five dogs with sinonasal aspergillosis, cribriform plate lysis diagnosed on CT scans, and normal neurologic examinations were treated with a single (n=3) or multiple (n=2) infusions of clotrimazole solution. No dogs developed clinical neurologic disease after therapy. Clinical significance In this study, a topical clotrimazole solution was not associated with adverse neurologic effects in neurologically normal dogs with sinonasal aspergillosis and cribriform plate lysis. |
| Databáze: | OpenAIRE |
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